| CAS N° |
name |
P/S/R |
date revision |
review |
amend. |
qra |
new |
explore details |
full version |
down-load |
93-15-2
Note box
The Standard is based on long-term systemic effects and will therefore have a wider range of product type limitations as follows:
Fine fragrance: 0.02%
Eau de toilette: 0.008%
Fragrancing cream: 0.004%
Other leave on: 0.0004%
Rinse-off: 0.001%
Non skin (as defined in the introduction to the Standards): 0.02%
Other non cosmetic products not covered above: 0.001%
The limitations apply to Methyleugenol (ME) originating from all sources. Contributions from essential oils can be significant. Names of essential oils, which should also be considered in the application of the Standard, are given below. Maximum percentage of the reference material is included for use when no analytical data is available.
Critical effect
Potential carcogenic activity in animals
|
Methyl eugenol |
R |
|
07 - 2007 |
36 |
|
 |
|
|
|
7493-74-5
Limits in the finished product (%)
| cat 1 |
0.02% - See Note box (1) |
cat 4 |
0.32% |
cat 7 |
0.05% |
cat 10 |
2.5% |
| cat 2 |
0.03% |
cat 5 |
0.17% |
cat 8 |
0.7% |
cat 11 |
See Note box (2) |
| cat 3 |
0.11% |
cat 6 |
0.51% |
cat 9 |
3.5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to negligible skin contact the concentration of a fragrance ingredient should not exceed the usual concentration of the fragrance compound in the finished product.
Please also refer to the IFRA Standard ALLYL ESTERS.
Purity requirement: Allyl esters should only be used when the level of free allylalcohol in the ester is less than 0.1%. This recommendation is based on the delayed irritant potential of allylalcohol.
Critical effect
SENSITIZATION
|
Allyl phenoxyacetate |
R |
2009 |
2014 |
44 |
|
|
|
|
|
101-85-9
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
1.6% |
cat 7 |
0.3% |
cat 10 |
2.5% |
| cat 2 |
0.1% |
cat 5 |
0.8% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.5% |
cat 6 |
2.5% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Amyl cinnamic alcohol |
R |
2007 |
2012 |
42 |
|
|
|
|
|
105-13-5
Limits in the finished product (%)
| cat 1 |
0.04% - See Note box (1) |
cat 4 |
0.7% |
cat 7 |
0.1% |
cat 10 |
2.5% |
| cat 2 |
0.1% |
cat 5 |
0.4% |
cat 8 |
1.5% |
cat 11 |
See Note box (2) |
| cat 3 |
0.2% |
cat 6 |
1.1% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofiorg.org).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Anisyl alcohol |
R |
2007 |
2012 |
42 |
|
|
|
|
|
100-51-6
Limits in the finished product (%)
| cat 1 |
0.2% - See Note box (1) |
cat 4 |
2.7% |
cat 7 |
0.4% |
cat 10 |
2.5% |
| cat 2 |
0.2% |
cat 5 |
1.4% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.9% |
cat 6 |
4.3% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Benzyl alcohol |
R |
2007 |
2012 |
42 |
|
|
|
|
|
120-51-4
Limits in the finished product (%)
| cat 1 |
1.7% - See Note box (1) |
cat 4 |
26.7% |
cat 7 |
4.5% |
cat 10 |
2.5% |
| cat 2 |
2.2% |
cat 5 |
14% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
8.9% |
cat 6 |
42.8% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Benzyl benzoate |
R |
2007 |
2012 |
42 |
|
|
|
|
|
103-41-3
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
2.1% |
cat 7 |
0.4% |
cat 10 |
2.5% |
| cat 2 |
0.2% |
cat 5 |
1.1% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.7% |
cat 6 |
3.4% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Benzyl cinnamate |
R |
2007 |
2012 |
42 |
|
|
|
|
|
140-29-4
Note box
The material as such should not be used as fragrance ingredient for any
application.
This material has previously been included in the list of 'Other Materials'; the material therefore has already been prohibited before.
Critical effect
RELEASE OF CYANIDE
|
Benzyl cyanide |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
118-58-1
Limits in the finished product (%)
| cat 1 |
0.5% - See Note box (1) |
cat 4 |
8% |
cat 7 |
1.3% |
cat 10 |
2.5% |
| cat 2 |
0.7% |
cat 5 |
4.2% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
2.7% |
cat 6 |
12.8% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Benzyl salicylate |
R |
2007 |
2012 |
42 |
|
|
|
|
|
8022-81-9
Critical effect
INSUFFICIENT DATA
|
Boldo oil |
P |
2009 |
|
44 |
|
|
|
|
|
Carvone: 99-49-0 d-Carvone: 2244-16-8 l-Carvone: 6485-40-1
Limits in the finished product (%)
| cat 1 |
0.08% - See Note box (1) |
cat 4 |
1.2% |
cat 7 |
0.2% |
cat 10 |
2.5% |
| cat 2 |
0.1% |
cat 5 |
0.6% |
cat 8 |
2% |
cat 11 |
Not Restricted (2) |
| cat 3 |
0.4% |
cat 6 |
1.9% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Carvone; d-Carvone; l-Carvone |
R |
2008 |
2013 |
43 |
|
|
|
|
|
33204-74-9
Note box
This material should not be used as fragrance ingredient for any application.
This material has previously been included in the list of ‘Other Materials’, the material therefore has already been prohibited before.
Critical effect
SENSITIZATION
|
Carvone oxide |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
4364-06-1
Limits in the finished product (%)
| cat 1 |
0.02% - See Note box (1) |
cat 4 |
0.37% |
cat 7 |
0.06% |
cat 10 |
2.5% |
| cat 2 |
0.03% |
cat 5 |
0.2% |
cat 8 |
0.8% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.12% |
cat 6 |
0.59% |
cat 9 |
4.1% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Cinnamic Aldehyde Dimethyl Acetal |
R |
2009 |
2014 |
44 |
|
|
|
|
|
106-22-9 1117-61-9 26489-01-0 6812-78-8 141-25-3 68916-43-8 7540-51-4
Limits in the finished product (%)
| cat 1 |
0.8% - See Note box (1) |
cat 4 |
13.3% |
cat 7 |
2.2% |
cat 10 |
2.5% |
| cat 2 |
1.1% |
cat 5 |
7% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
4.4% |
cat 6 |
21.4% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofiorg.org).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Citronellol |
R |
2007 |
2012 |
42 |
|
|
|
|
|
91-64-5
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
1.6% |
cat 7 |
0.3% |
cat 10 |
2.5% |
| cat 2 |
0.13% |
cat 5 |
0.8% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.5% |
cat 6 |
2.5% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Coumarin |
R |
2008 |
2013 |
43 |
|
|
|
|
|
103-50-4
Limits in the finished product (%)
| cat 1 |
0.07% - See Note box (1) |
cat 4 |
1.04% |
cat 7 |
0.17% |
cat 10 |
2.5% |
| cat 2 |
0.08% |
cat 5 |
0.55% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.35% |
cat 6 |
1.67% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry
http://www.iofiorg.org/)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Dibenzyl ether |
R |
2009 |
2014 |
44 |
|
|
|
|
|
56973-85-4
Limits in the finished product (%)
| cat 1 |
0.07% - See Note box (1) |
cat 4 |
1.13% |
cat 7 |
0.19% |
cat 10 |
2.5% |
| cat 2 |
0.09% |
cat 5 |
0.6% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.38% |
cat 6 |
1.81% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry
http://www.iofiorg.org/)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
1-(5,5-Dimethyl-1-cyclohexen-1-yl)pent-4-en-1-one |
R |
2009 |
2014 |
44 |
|
|
|
|
|
40607-48-5
Note box
This material should not be used as fragrance ingredient for any application.
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SENSITIZATION
|
3,7-Dimethyl-2-octen-1-ol |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
2563-07-7
Limits in the finished product (%)
| cat 1 |
0.01% - See Note box (1) |
cat 4 |
0.1% |
cat 7 |
0.02% |
cat 10 |
1.9% |
| cat 2 |
0.01% |
cat 5 |
0.1% |
cat 8 |
0.2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.03% |
cat 6 |
0.2% |
cat 9 |
1.2% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry
http://www.iofiorg.org/)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
2-Ethoxy-4-methylphenol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
110-80-5 111-15-9 (acetate)
Note box
This material should not be used as fragrance ingredient for any application.
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
REPRODUCTIVE TOXICITY
|
Ethylene glycol monoethyl ether and its acetate |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
109-86-4 110-49-6 (acetate)
Note box
This material should not be used as fragrance ingredient for any application.
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
REPRODUCTIVE TOXICITY
|
Ethylene glycol monomethyl ether and its acetate |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
98-00-0
Critical effect
INSUFFICIENT DATA
|
Furfuryl Alcohol |
P |
2009 |
|
44 |
|
|
|
|
|
106-24-1
Limits in the finished product (%)
| cat 1 |
0.3% - See Note box (1) |
cat 4 |
5.3% |
cat 7 |
0.9% |
cat 10 |
2.5% |
| cat 2 |
0.4% |
cat 5 |
2.8% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
1.8% |
cat 6 |
8.6% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (http://www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Geraniol |
R |
2007 |
2012 |
42 |
|
|
|
|
|
6259-76-3
Limits in the finished product (%)
| cat 1 |
1% - See Note Box (1) |
cat 4 |
16% |
cat 7 |
2.7% |
cat 10 |
2.5% |
| cat 2 |
1.3% |
cat 5 |
8.4% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
5.3% |
cat 6 |
25.7% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (http://www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Hexyl salicylate |
R |
2007 |
2012 |
42 |
|
|
|
|
|
6658-48-6
Limits in the finished product (%)
| cat 1 |
0.07% - See Note Box (1) |
cat 4 |
1.04% |
cat 7 |
0.17% |
cat 10 |
2.5% |
| cat 2 |
0.08% |
cat 5 |
0.55% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.35% |
cat 6 |
1.67% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-Isobutyl-alpha-methyl hydrocinnamaldehyde |
R |
2009 |
2014 |
44 |
|
|
|
|
|
65505-24-0
Note box
The material has been identified for having the potential of forming nitrosamines in nitrosating systems. Downstream users therefore have to be notified of the presence of the material and its potential to be able to consider adequate protective measures.
Critical effect
POTENTIAL OF NITROSAMINE FORMATION
|
Isobutyl N-methylanthranylate |
R |
2009 |
2014 |
44 |
|
|
|
|
|
1335-66-6 1423-46-7 67634-07-5
Limits in the finished product (%)
| cat 1 |
0.2% - See Note Box (1) |
cat 4 |
3.2% |
cat 7 |
0.5% |
cat 10 |
2.5% |
| cat 2 |
0.3% |
cat 5 |
1.7% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
1.1% |
cat 6 |
5.1% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Isocyclocitral |
R |
2007 |
2012 |
42 |
|
|
|
|
|
91770-14-8
Limits in the finished product (%)
| cat 1 |
0.25% - See Note Box (1) |
cat 4 |
4% |
cat 7 |
0.7% |
cat 10 |
2.5% |
| cat 2 |
0.32% |
cat 5 |
2.1% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
1.33% |
cat 6 |
6.4% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Jasmine absolute (sambac) |
R |
2008 |
2013 |
43 |
|
|
|
|
|
101-39-3
Limits in the finished product (%)
| cat 1 |
0.1% - See Note Box (1) |
cat 4 |
1.6% |
cat 7 |
0.3% |
cat 10 |
2.5% |
| cat 2 |
0.1% |
cat 5 |
0.8% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.5% |
cat 6 |
2.5% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Methyl cinnamic aldehyde |
R |
2007 |
2012 |
42 |
|
|
|
|
|
93-08-3
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products. If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Methyl beta-naphthyl ketone |
R |
2004 |
2009 |
39 |
|
|
|
|
|
91-61-2
Note box
The material has been identified for having the potential of forming nitrosamines in nitrosating systems. Downstream users therefore have to be notified of the presence of the material and its potential to be able to consider adequate protective measures.
Critical effect
POTENTIAL FOR NITROSAMINE FORMATION
|
p-Methyltetrahydroquinoline IFRA |
R |
2009 |
2014 |
44 |
|
|
|
|
|
| 81-15-2
|
Musk xylene |
P |
2009 |
|
44 |
|
|
|
|
|
54464-57-2
Limits in the finished product (%)
| cat 1 |
1.34% - See Note Box (1) |
cat 4 |
21.4% |
cat 7 |
3.6% |
cat 10 |
2.5% |
| cat 2 |
1.73% |
cat 5 |
11.2% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
7.1% |
cat 6 |
34.2% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
OTNE (1-(1,2,3,4,5,6,7,8 Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone) |
R |
2008 |
2013 |
43 |
|
|
|
|
|
93-53-8
Limits in the finished product (%)
| cat 1 |
0.01% - See Note Box (1) |
cat 4 |
0.17% |
cat 7 |
0.03% |
cat 10 |
2.5% |
| cat 2 |
0.01% |
cat 5 |
0.09% |
cat 8 |
0.4% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.06% |
cat 6 |
0.28% |
cat 9 |
1.9% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to negligible skin contact the concentration of a fragrance ingredient should not exceed the usual concentration of the fragrance compound in the finished product.
Critical effect
SENSITIZATION
|
2-Phenylpropionaldehyde |
R |
2009 |
2014 |
44 |
|
|
|
|
|
19343-78-3
Note box
The material has been identified for having the potential of forming nitrosamines in nitrosating systems. Downstream users therefore have to be notified of the presence of the material and its potential to be able to consider adequate protective measures.
Critical effect
POTENTIAL OF NITROSAMINE FORMATION
|
1,2,3,4-Tetrahydro-4-methylquinoline |
P |
2009 |
2014 |
44 |
|
|
|
|
|
117-98-6 62563-80-8 68917-34-0 73246-97-6 84082-84-8
Limits in the finished product (%)
| cat 1 |
0.07% - See Note Box (1) |
cat 4 |
1.04% |
cat 7 |
0.17% |
cat 10 |
2.5% |
| cat 2 |
0.08% |
cat 5 |
0.55% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.35% |
cat 6 |
1.67% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to negligible skin contact the concentration of a fragrance ingredient should not exceed the usual concentration of the fragrance compound in the finished product.
Acetylated vetiver oil (Vetiveryl acetate) should only be used as a fragrance ingredient if produced by methods that lead to a reduction in allergenic materials, like the ones outlined below (acetylation methods using acetic anhydride):
without catalyst, at a temperature not exceeding 120°C.
with ortho phosphoric acid at room temperature.
with sodium acetate in toluene at reflux temperature.
The first two products can be used in their crude form after the usual procedures, but may be further purified. In the last case, distillation is necessary.
Another method accepted is an enzymatic acetylation process.
This recommendation is based on test results of RIFM with samples prepared according to different acetylation methods (private communication to IFRA).
Critical effect
SENSITIZATION
|
Vetiveryl acetate |
R |
2009 |
2014 |
44 |
|
|
|
|
|
8006-81-3 68606-83-7 83863-30-3
Limits in the finished product (%)
| cat 1 |
0.05% - See Note Box (1) |
cat 4 |
0.8% |
cat 7 |
0.1% |
cat 10 |
2.5% |
| cat 2 |
0.06% |
cat 5 |
0.4% |
cat 8 |
1.8% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.27% |
cat 6 |
1.3% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) http://www.iofiorg.org/.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Ylang Ylang Extracts |
R |
2008 |
2013 |
43 |
|
|
|
|
|
13144-88-2
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.24% |
cat 8 |
1.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.15% |
cat 6 |
0.72% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
1-(2,4,4,5,5-Pentamethyl-1-cyclopenten-1-yl)ethan-1-one |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
39189-74-7
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.24% |
cat 8 |
1.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.15% |
cat 6 |
0.72% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
2-Heptylidene cyclopentan-1-one |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
13257-44-8
Limits in the finished product (%)
| cat 1 |
0.66% - See Note Box (1) |
cat 4 |
10.41% |
cat 7 |
1.74% |
cat 10 |
2.5% |
| cat 2 |
0.84% |
cat 5 |
5.48% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
3.47% |
cat 6 |
16.67% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
2-Nonyn-1-al dimethyl acetal |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
68922-13-4
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.5% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.26% |
cat 8 |
1.11% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.17% |
cat 6 |
0.8% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
3-Methyl-2-(pentyloxy)cyclopent-2-en-1-one |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
16251-77-7
Limits in the finished product (%)
| cat 1 |
0.17% - See Note Box (1) |
cat 4 |
2.7% |
cat 7 |
0.45% |
cat 10 |
2.5% |
| cat 2 |
0.22% |
cat 5 |
1.4% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.89% |
cat 6 |
4.3% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
3-Phenylbutanal |
R |
06 - 2010 |
2015 |
45 |
|
|
|
|
|
7492-44-6
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.24% |
cat 8 |
1.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.15% |
cat 6 |
0.72% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Butylcinnamaldehyde |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
1504-74-1
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.24% |
cat 8 |
1.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.15% |
cat 6 |
0.72% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
o-Methoxycinnamaldehyde |
R |
06 - 2011 |
2016 |
46 |
|
|
|
|
|
91-22-5
Note box
The material is considered as a carcinogenic / mutagenic agent and had only minor reported use in fragrances.
REXPAN agreed to the IFRA policy to ban the material for the given effects and not further elaborate on a risk management policy.
Critical effect
CARCINOGENICITY, MUTAGENICITY
|
Quinoline |
P |
06 - 2010 |
|
45 |
|
|
|
|
|
Including but not limited to: 764-40-9 142-83-6 80466-34-8 5910-85-0 30361-28-5 6750-03-4 2363-88-4
Note box
This IFRA Standard represents the group of 2-4-Dienals and replaces the existing individual IFRA Standards for the materials listed above. This new group also includes any other 2,4-Dienals. Note that 2,4-Hexadienal, 2,4-Heptadienal, 2,4-Octadienal, 2,4-Nonadienal, 2,4-Decadienal and 2,4-Undecadienal have already been banned via individual IFRA Standards therefore no implementation time is necessary. For all other 2,4-dienals (such as 2,4-Pentadienal and 2,4-Dodecadienal), the implementation date is Month Day, 2013 for new submissions and Month Day, 2014 for existing fragrance compounds.
Critical effect
INSUFFICIENT DATA
|
2,4-Dienals |
P |
06 - 2013 |
|
47 |
|
|
|
|
|
122-03-2
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.5% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.26% |
cat 8 |
1.11% |
cat 11 |
See Note box (2) |
| cat 3 |
0.17% |
cat 6 |
0.8% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Cuminaldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
103-95-7
Limits in the finished product (%)
| cat 1 |
0.17% - See Note box (1) |
cat 4 |
2.67% |
cat 7 |
0.45% |
cat 10 |
2.5% |
| cat 2 |
0.22% |
cat 5 |
1.4% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.89% |
cat 6 |
4.28% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Cyclamen aldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
106-02-5
Limits in the finished product (%)
| cat 1 |
0.16% - See Note box (1) |
cat 4 |
2.5% |
cat 7 |
0.42% |
cat 10 |
2.5% |
| cat 2 |
0.2% |
cat 5 |
1.31% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.83% |
cat 6 |
3.93% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Cyclopentadecanolide |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
98-01-1
Note box
These restrictions are not based on dermal sensitization QRA.
(1) The non skin contact level should apply to the same product types as contained in QRA category 11, which includes all non-skin contact or incidental skin contact products.
Critical effect
CARCINOGENICITY
|
Furfural |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
529-20-4 620-23-5 104-87-0 1334-78-7
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.5% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.26% |
cat 8 |
1.11% |
cat 11 |
See Note box (2) |
| cat 3 |
0.17% |
cat 6 |
0.8% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
o,m,p-Tolualdehydes and their mixtures |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
8021-36-1 9000-78-6 93384-32-8
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
0.6% |
| cat 2 |
0.04% |
cat 5 |
0.24% |
cat 8 |
0.6% |
cat 11 |
See Note box (2) |
| cat 3 |
0.15% |
cat 6 |
0.6% |
cat 9 |
0.6% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Opoponax oil can be obtained from solvent extraction or pyrolysis.
Opoponax oil obtained through pyrolysis shall be rectified according to Good Manufacturing Practices and the content of polynuclear aromatic hydrocarbons (PAH) resulting from their use shall respect the following requirement:
Benzopyrene and 1,2-Benzanthracene are to be used as markers for PAH. If used alone or in combination with rectified Cade oil, rectified Birch tar oils or rectified Styrax oil, the total concentration of both of the markers should not exceed 1 ppb in the final product.
Critical effect
SENSITIZATION
|
Opoponax (all forms) |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
4748-78-1
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.5% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.04% |
cat 5 |
0.26% |
cat 8 |
1.11% |
cat 11 |
See Note box (2) |
| cat 3 |
0.17% |
cat 6 |
0.8% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-Ethylbenzaldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
123-11-5
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
1.61% |
cat 7 |
0.27% |
cat 10 |
2.5% |
| cat 2 |
0.13% |
cat 5 |
0.84% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.54% |
cat 6 |
2.53% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-Methoxybenzaldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
8046-19-3 8024-01-9 94891-27-7 94981-28-8
Limits in the finished product (%)
| cat 1 |
0.04% - See Note box (1) |
cat 4 |
0.6% |
cat 7 |
0.11% |
cat 10 |
0.6% |
| cat 2 |
0.05% |
cat 5 |
0.36% |
cat 8 |
0.6% |
cat 11 |
See Note box (2) |
| cat 3 |
0.23% |
cat 6 |
0.6% |
cat 9 |
0.6% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Crude gums of Liquidambar styraficula L. var. macrophylla or Liquidambar orientalis Mill. should not be used as fragrance ingredients: Only extracts or distillates (resinoids, absolutes and oils), prepared from exudations of Liquidambar styraciflua L. var. macrophylla or Liquidambar orientalis Mill., can be used.This recommendation is made in order to promote good manufacturing practice (GMP) for the use of styrax derivatives as fragrance ingredients. It is based on a wide variety of RIFM test data with gums, resinoids, absolutes and oils of American and Asian styrax (private communication to IFRA).
In addition, Styrax oil can be obtained from solvent extraction or pyrolysis.
Styrax oil obtained through pyrolysis shall be rectified according to Good Manufacturing Practices and the content of polynuclear aromatic hydrocarbons (PAH) resulting from their use shall respect the following requirement:
Benzopyrene and 1,2-Benzanthracene are to be used as markers for PAH. If used alone or in combination with rectified Cade oil, rectified Birch tar oils or rectified Opoponax oil, the total concentration of both of the markers should not exceed 1 ppb in the final product.
Critical effect
SENSITIZATION
|
Styrax |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
140-67-0
Note box
The total concentration of Estragole should not exceed the following limitations in
the finished product:
Fine fragrance and Eau de Toilette: 0.2%
Other leave on and rinse-off cosmetic products: 0.01%
Non skin and non cosmetic products: 0.2%
Critical effect
CARCINOGENICITY
|
Estragole |
R |
2009 |
2014 |
44 |
|
|
|
|
|
88-29-9
Critical effect
NEUROTOXICITY
|
Acetyl ethyl tetramethyl tetralin |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
15323-35-0
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Acetyl-1,1,2,3,3,6-hexamethyl indan (AHMI) |
R |
09 - 2001 |
2006 |
39 |
|
|
|
|
|
13706-86-0
Critical effect
SENSITIZATION
|
Acetyl isovaleryl (5-Methyl-2,3-hexanedione) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
97676-35-2
Critical effect
SENSITIZATION
|
Alantroot oil (Elecampane oil) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
Note box
Allyl esters should only be used when the level of free allylalcohol in the ester is less than 0.1%. This recommendation is based on the delayed irritant potential of allylalcohol.
Critical effect
SEE FRAGRANCE MATERIAL SPECIFICATION
|
Allyl esters |
S |
2009 |
|
44 |
|
|
|
|
|
73157-43-4
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Allyl heptine carbonate |
P |
05 - 2007 |
|
43 |
|
|
|
|
|
57-06-7
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Allyl isothiocyanate |
P |
|
|
43 |
|
|
|
|
|
8015-64-3
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Angelica root oil |
R |
09 - 2001 |
2006 |
39 |
|
|
|
|
|
25564-22-1
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Amylcyclopentenone |
P |
05 - 2007 |
|
43 |
|
|
|
|
|
943-88-4
Critical effect
SENSITIZATION
|
Anisylidene acetone (4-(p-methoxyphenyl)-3-butene-2-one) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
2883-98-9 5273-86-9
Note box
cis- and trans-Asarone as such should not be used as fragrance ingredients;
essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in
consumer products.
This recommendation is based on similar biological effects to those of safrole (R.W.
Wiseman, E.C. Miller et al. (1987), Cancer Res. 47,2275-2283).
Critical effect
SEE NOTE BOX
|
cis-and trans-Asarone ((E)-and(Z)-2,4,5-Trimethoxypropen-1-ylbenzene) |
R |
12 - 1991 |
|
40 |
|
|
|
|
|
71-43-2
Note box
The material should not be used as fragrance ingredient for any application.
The level of benzene has to be kept as low as practicable and should never exceed 1 ppm in the fragrance compound.
Since the introduction of the original restriction on the use of benzene by IFRA in 1988, there have been significant changes in manufacturing practices that permit the reduction of the maximum permitted level of this substance. These include use of technological improvements allowing replacement of this solvent for the extraction of fragrance materials and in eliminating its presence as an impurity in alternative extraction solvents.
Critical effect
CARCINOGENICITY
|
Benzene |
P |
01 - 2004 |
|
38 |
|
|
|
|
|
122-57-6
Critical effect
SENSITIZATION
|
Benzylidene acetone (4-Phenyl-3-buten-2-one) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
908007-75-8
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Bergamot oil expressed |
R |
06 - 1992 |
|
|
|
|
|
|
|
68916-04-1 72968-50-4
Note box
Applications on skin areas exposed to sunshine.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic fragrance ingredients, expressed in % of their recommended maximum level in the consumer product, shall not exceed 100.
For Bitter Orange Peel Oil Expressed, the general Standard on 'Citrus oils and other furocoumarin containing essential oils' also needs to be taken into account.
Critical effect
PHOTOIRRITATION
|
Bitter orange peel oil expressed |
R |
07 - 2002 |
07 - 2007 |
36 |
|
|
|
|
|
76-29-9
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
3-Bromo-1,7,7-trimethylbicyclo[2.2.1]heptane-2-one |
P |
|
|
43 |
|
|
|
|
|
103-64-0
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Bromostyrene |
P |
|
|
43 |
|
|
|
|
|
18127-01-0
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.5% |
cat 7 |
0.1% |
cat 10 |
0.6% |
| cat 2 |
0.04% |
cat 5 |
0.3% |
cat 8 |
0.6% |
cat 11 |
Not Restricted (2) |
| cat 3 |
0.2% |
cat 6 |
0.8% |
cat 9 |
0.6% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-tert-Butyldihydrocinnamaldehyde (Bourgeonal) |
R |
2008 |
2013 |
43 |
|
|
|
|
|
98-54-4
Critical effect
SENSITIZATION, DEPIGMENTATION
|
p-tert-Butylphenol |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
8006-99-3
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Chenopodium oil |
P |
|
|
43 |
|
|
|
|
|
104-54-1
Limits in the finished product (%)
| cat 1 |
0.09% - See Note box (1) |
cat 4 |
0.4% |
cat 7 |
0.2% |
cat 10 |
0.4% |
| cat 2 |
0.1% |
cat 5 |
0.4% |
cat 8 |
0.4% |
cat 11 |
Not Restricted (2) |
| cat 3 |
0.4% |
cat 6 |
2.2% |
cat 9 |
0.4% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
There is also a separate Standard for Styrax that should be taken into account.
Critical effect
SENSITIZATION
|
Cinnamic alcohol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
4173-44-8
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Cinnamylidene acetone |
P |
|
|
43 |
|
|
|
|
|
1885-38-7 4360-47-8
Limits in the finished product (%)
| cat 1 |
0.03% - See Note box (1) |
cat 4 |
0.125% |
cat 7 |
0.08% |
cat 10 |
0.125% |
| cat 2 |
0.04% |
cat 5 |
0.125% |
cat 8 |
0.125% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.125% |
cat 6 |
0.8% |
cat 9 |
0.125% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
(http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Cinnamyl nitrile |
R |
2008 |
2013 |
43 |
|
|
|
|
|
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Citrus oils and other furocoumarins containing essential oils |
R |
12 - 1996 |
|
|
|
|
|
|
|
8050-09-7
Critical effect
SENSITIZATION
|
Colophony |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
8023-88-9
Critical effect
SENSITIZATION
|
Costus root oil, absolute and concrete |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
8014-13-9
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Cumin oil |
R |
09 - 2001 |
2010 |
39 |
|
|
|
|
|
4756-19-8
Note box
Cyclamen alcohol should not be used as a fragrance ingredient as such, but a level of up to 1.5% in cyclamen aldehyde is accepted.
Critical effect
SENSITIZATION
|
Cyclamen alcohol (3-(4-Isopropylphenyl)-2-methylpropanol) |
P |
10 - 1978 |
|
|
|
|
|
|
|
63697-53-0
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
1,3-Dibromo-2-methoxy-4-nitro-5-(1,1-dimethylethyl)-6-methyl-benzene (Musk Alpha) |
P |
|
|
43 |
|
|
|
|
|
62265-99-0
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
1,3-Dibromo-2-methoxy-4-methyl-5-nitrobenzene (Musk KS) |
P |
|
|
43 |
|
|
|
|
|
3591-42-2
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
2,2-Dichloro-1-methylcyclopropylbenzene |
P |
|
|
43 |
|
|
|
|
|
141-05-9
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SENSITIZATION
|
Diethyl maleate |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
6248-20-0
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SENSITIZATION
|
2,4-Dihydroxy-3-methylbenzaldehyde |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
17874-34-9
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
PHOTOALLERGY
|
4,6-Dimethyl-8-tert-butylcoumarin |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
617-54-9
Critical effect
SENSITIZATION
|
Dimethyl citraconate |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
122-39-4
Note box
This material should not be used as fragrance ingredient for any application.
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
TOXICITY, TERATOGENICITY
|
Diphenylamine |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
10484-32-9 10519-20-7
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Methyl heptine carbonate is not Prohibited because it is IFRA Restricted.
Critical effect
SEE NOTE BOX
|
Esters of 2-octynoic acid (Except for methyl heptine carbonate) |
P |
|
|
43 |
|
|
|
|
|
10031-92-2
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Methyl octine carbonate is not Prohibited because it is IFRA Restricted.
Critical effect
SEE NOTE BOX
|
Esters of 2-nonynoic acid (Except Methyl Octine Carbonate) |
P |
|
|
43 |
|
|
|
|
|
140-88-5
Critical effect
SENSITIZATION
|
Ethyl acrylate |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
97-53-0
Limits in the finished product (%)
| cat 1 |
0.2% - See Note box (1) |
cat 4 |
0.5% |
cat 7 |
0.4% |
cat 10 |
0.5% |
| cat 2 |
0.2% |
cat 5 |
0.5% |
cat 8 |
0.5% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.5% |
cat 6 |
4.3% |
cat 9 |
0.5% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Eugenol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
4602-84-0
Limits in the finished product (%)
| cat 1 |
0.08% |
cat 4 |
1.2% |
cat 7 |
0.2% |
cat 10 |
2.5% |
| cat 2 |
0.11% |
cat 5 |
0.6% |
cat 8 |
2% |
cat 11 |
See Note Box |
| cat 3 |
0.4% |
cat 6 |
2% |
cat 9 |
5% |
|
|
Note box
Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
This Standard replaces the existing one on Farnesol, which only contained the purity criterion as outlined below:
Farnesol should only be used as a fragrance ingredient if it contains a minimum of 96% of
farnesol isomers as determined by GLC.
Critical effect
SENSITIZATION
|
Farnesol |
R |
2006 |
2011 |
40 |
|
|
|
|
|
68916-52-9
Critical effect
SENSITIZATION, PHOTOTOXICITY
|
Fig leaf absolute |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
623-15-4
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Furfurylidene acetone |
P |
|
|
43 |
|
|
|
|
|
5146-66-7 5585-39-7 31983-27-4
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Geranyl nitrile |
P |
11 - 2006 |
|
43 |
|
|
|
|
|
8016-20-4
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
For applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, grapefruit oil expressed should not be used such that the level in the consumer products exceeds 4%.
Note: See remark on phototoxic ingredients in the introduction to the Standards (Appendix 8 to the IFRA Code of Practice) and the Standard on Citrus oil and other furocoumarinscontaining essential oils.
For qualities of the expressed oil in which the less volatile components have been concentrated by partial or total removal of the terpene fraction, this limit should be reduced in proportion to the degree of concentration.
Critical effect
PHOTOTOXICITY
|
Grapefruit oil expressed |
R |
06 - 1992 |
|
|
|
|
|
|
|
18829-55-5
Critical effect
SENSITIZATION
|
trans-2-Heptenal |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
700-82-3
Critical effect
SENSITIZATION
|
Hexahydrocoumarin |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
6728-26-3
Limits in the finished product (%)
| cat 1 |
0.001% - See Note Box (1) |
cat 4 |
0.002% |
cat 7 |
0.002% |
cat 10 |
0.002% |
| cat 2 |
0.001% |
cat 5 |
0.002% |
cat 8 |
0.002% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.002% |
cat 6 |
0.02% |
cat 9 |
0.002% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (http://www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
trans-2-Hexenal |
R |
2008 |
2013 |
43 |
|
|
|
|
|
67746-30-9
Critical effect
SENSITIZATION
|
trans-2-Hexenal diethyl acetal |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
18318-83-7
Critical effect
SENSITIZATION
|
trans-2-Hexenal dimethyl acetal |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
17373-89-6
Limits in the finished product (%)
| cat 1 |
0.01% - See Note Box (1) |
cat 4 |
0.06% |
cat 7 |
0.02% |
cat 10 |
0.06% |
| cat 2 |
0.01% |
cat 5 |
0.06% |
cat 8 |
0.06% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.05% |
cat 6 |
0.2% |
cat 9 |
0.06% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (http://www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Hexylidene cyclopentanone |
R |
2008 |
2013 |
43 |
|
|
|
|
|
13393-93-6 26266-77-3 1333-89-7
Note box
So far only the use in cosmetic products was banned. This ban is now extended to all kinds of fragrance application (use).
Critical effect
SENSITIZATION
|
Hydroabietyl alcohol, Dihydroabietyl alcohol |
P |
05 - 2003 |
|
38 |
|
|
|
|
|
622-62-8
Note box
So far only the use in cosmetic products was banned. This ban is now extended to all kinds of fragrance application (use).
Critical effect
DEPIGMENTATION
|
Hydroquinone monoethyl ether (4-ethoxy-Phenol) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
150-76-5
Critical effect
DEPIGMENTATION
|
Hydroquinone monomethyl ether (4-methoxy-Phenol) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
68527-77-5
Limits in the finished product (%)
| cat 1 |
0.11% - See Note Box (1) |
cat 4 |
0.5% |
cat 7 |
0.3% |
cat 10 |
0.5% |
| cat 2 |
0.14% |
cat 5 |
0.5% |
cat 8 |
0.5% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.5% |
cat 6 |
2.8% |
cat 9 |
0.5% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Isocyclogeraniol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
97-54-1
Limits in the finished product (%)
| cat 1 |
0.01% - See Note Box (1) |
cat 4 |
0.02% |
cat 7 |
0.02% |
cat 10 |
0.02% |
| cat 2 |
0.01% |
cat 5 |
0.02% |
cat 8 |
0.02% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.02% |
cat 6 |
0.2% |
cat 9 |
0.02% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Isoeugenol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
78-59-1
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Isophorone |
P |
|
|
43 |
|
|
|
|
|
34131-99-2
Critical effect
SENSITIZATION
|
6-Isopropyl-2-decalol (Decatol) |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
8022-96-6 8024-43-9 90045-94-6 84776-64-7
Limits in the finished product (%)
| cat 1 |
0.04% - See Note Box (1) |
cat 4 |
0.7% |
cat 7 |
0.1% |
cat 10 |
2.5% |
| cat 2 |
0.05% |
cat 5 |
0.4% |
cat 8 |
1.5% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.22% |
cat 6 |
1.1% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Jasmine absolute (grandiflorum) |
R |
2008 |
2013 |
43 |
|
|
|
|
|
8008-56-8
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
For applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, lemon oil cold pressed should not be used such that the level in the consumer products exceeds 2%.
Note: See remark on phototoxic ingredients in the introduction to the Standards (Appendix 8 to the IFRA Code of Practice) and the Standard on Citrus oil and other furocoumarins containing essential oils.
For qualities of the expressed oil in which the less volatile components have been concentrated by partial or total removal of the terpene fraction, this limit should be reduced in proportion to the degree of concentration.
Critical effect
PHOTOTOXICITY
|
Lemon oil cold pressed |
R |
06 - 1992 |
|
|
|
|
|
|
|
8008-26-2
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
For applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, lime oil expressed should not be used such that the level in the consumer products exceeds 0.7%.
Note: See remark on phototoxic ingredients in the introduction to the Standards (Appendix 8 to the IFRA Code of Practice) and the Standard on Citrus oil and other furocoumarins containing essential oils.
For qualities of the expressed oil in which the less volatile components have been concentrated by partial or total removal of the terpene fraction, this limit should be reduced in proportion to the degree of concentration.
Critical effect
PHOTOTOXICITY
|
Lime oil expressed |
R |
06 - 1992 |
|
|
|
|
|
|
|
138-86-3
Note box
d-, l-and dl-Limonene and natural products containing substantial amounts of it, should only be used when the level of peroxides is kept to the lowest practical level, for instance by adding antioxidants at the time of production. Such products should have a peroxide value of less than 20 millimoles peroxides per liter, determined according to the FMA method, which can be downloaded from the IFRA website (see Analytical Methods).
Critical effect
SENSITIZATION
|
Limonene |
S |
12 - 1995 |
|
|
|
|
|
|
|
78-70-6 126-90-9 (d-linalool) 126-91-0 (l-linalool)
Note box
Limit peroxide level to 20 mmol/l.
Linalool and natural products known to be rich in linalool, such as bois de rose, coriander or ho wood oil, should only be used when the level of peroxides is kept to the lowest practical level. It is recommended to add antioxidants at the time of production of the raw material. The addition of 0.1% BHT or alpha-tocopherol for example has shown great efficiency. The maximum peroxide level for products in use should be 20 mmol/l.
The (hydro) peroxide content can be determined by using the FMA method.
Critical effect
SENSITIZATION
|
Linalool |
S |
11 - 2003 |
|
38 |
|
|
|
|
|
85085-26-3
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Massoia bark oil |
P |
|
|
43 |
|
|
|
|
|
54814-64-1
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Massoia lactone |
P |
|
|
43 |
|
|
|
|
|
8014-71-9 84082-61-1
Limits in the finished product (%)
| cat 1 |
0.04% - See Note Box (1) |
cat 4 |
0.63% |
cat 7 |
0.11% |
cat 10 |
2.5% |
| cat 2 |
0.05% |
cat 5 |
0.33% |
cat 8 |
1.4% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.21% |
cat 6 |
1.01% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Melissa oil (genuine Melissa officinalis L.) |
R |
2009 |
2014 |
44 |
|
|
|
|
|
68683-20-5
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.1% |
cat 7 |
0.08% |
cat 10 |
0.1% |
| cat 2 |
0.04% |
cat 5 |
0.1% |
cat 8 |
0.1% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.1% |
cat 6 |
0.8% |
cat 9 |
0.1% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Menthadiene-7-methyl formate |
R |
2008 |
2013 |
43 |
|
|
|
|
|
531-59-9
Note box
The material as such should not be used as a fragrance ingredient for any application.
On the basis of established maximum levels of this substance in commercially available natural sources (like essential oils, extracts and absolutes), exposure to this substance from the use of these oils and extracts is regarded acceptable as long as the level of 7-Methoxy-coumarin in the finished product does not exceed 100 ppm.
Furthermore, these natural extracts should not be used as substitutes for this substance.
Examples for potential natural sources (with indicative maximum levels) of 7-Methoxycoumarin are:
Camomilla matricaria EO 0,1 %
Camomilla matricaria absolute (volatile part) : 5 %
Lavandin absolute: 5 % (on the total absolute).
Lavander and lavandin essential oils : <0,02 %
Lavender absolute: 5 % (on the total absolute).
Lime cold pressed oil: 0,1 %
Tarragon absolute: volatile part: 5 %
Tarragon essential oil : <0,1 %
Critical effect
SENSITIZATION, PHOTOSENSITIZATION
|
7-Methoxycoumarin |
P |
2008 |
2013 |
43 |
|
|
|
|
|
86803-90-9
Limits in the finished product (%)
| cat 1 |
0.1% - See Note Box (1) |
cat 4 |
0.5% |
cat 7 |
0.4% |
cat 10 |
0.5% |
| cat 2 |
0.2% |
cat 5 |
0.5% |
cat 8 |
0.5% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.5% |
cat 6 |
3.6% |
cat 9 |
0.5% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Methoxy dicyclopentadiene carboxaldehyde (Scentenal) |
R |
2008 |
2013 |
43 |
|
|
|
|
|
93-51-6
Limits in the finished product (%)
| cat 1 |
0.003% - See Note Box (1) |
cat 4 |
0.01% |
cat 7 |
0.009% |
cat 10 |
0.01% |
| cat 2 |
0.004% |
cat 5 |
0.01% |
cat 8 |
0.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.01% |
cat 6 |
0.09% |
cat 9 |
0.01% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
2-Methoxy-4-methylphenol |
R |
2008 |
2013 |
43 |
|
|
|
|
|
104-27-8
Critical effect
SENSITIZATION
|
alpha-Methyl anisylidene acetone |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
92-48-8
Critical effect
PHOTOALLERGY
|
6-Methylcoumarin |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
2445-83-2
Critical effect
SENSITIZATION, PHOTOALLERGY
|
7-Methylcoumarin |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
623-43-8
Critical effect
SENSITIZATION
|
Methyl crotonate |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
87-05-8
Critical effect
PHOTOALLERGY
|
4-Methyl-7-ethoxycoumarin |
P |
09 - 2012 |
|
40 |
|
|
|
|
|
1604-28-0
Limits in the finished product (%)
| cat 1 |
0.002% - See Note Box (1) |
cat 4 |
0.002% |
cat 7 |
0.002% |
cat 10 |
0.002% |
| cat 2 |
0.002% |
cat 5 |
0.002% |
cat 8 |
0.002% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.002% |
cat 6 |
0.1% |
cat 9 |
0.002% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
6-Methyl-3,5-heptadien-2-one |
R |
2009 |
2014 |
44 |
|
|
|
|
|
111-12-6
Limits in the finished product (%)
| cat 1 |
0.003% - See Note Box (1) |
cat 4 |
0.01% |
cat 7 |
0.008% |
cat 10 |
0.01% |
| cat 2 |
0.004% |
cat 5 |
0.01% |
cat 8 |
0.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.01% |
cat 6 |
0.08% |
cat 9 |
0.01% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
When used in the same fragrance compound within a specific QRA category, the sum total of methyl heptine carbonate (MHC) and methyl octine carbonate (MOC) contributions must not exceed the maximum permitted level for MHC. At the same time, the contribution from methyl octine carbonate should always respect the maximum levels permitted in the respective categories as listed in the Standard for MOC. If the same compound is intended for more than one IFRA QRA category, then the most restrictive limitations (based on foreseen use concentrations and maximum permitted level) will apply.
Critical effect
SENSITIZATION
|
Methyl heptine carbonate |
R |
2008 |
2013 |
43 |
|
|
|
|
|
5406-12-2
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
p-Methylhydrocinnamic aldehyde |
P |
05 - 2007 |
|
43 |
|
|
|
|
|
1335-46-2 127-42-4 127-43-5 127-51-5 7779-30-8
Limits in the finished product (%)
| cat 1 |
2% - See Note Box (1) |
cat 4 |
31.7% |
cat 7 |
5.3% |
cat 10 |
2.5% |
| cat 2 |
2.6% |
cat 5 |
16.7% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
10.6% |
cat 6 |
50.7% |
cat 9 |
5% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
The above limits apply to methyl ionone isomers used individually or in combination.
Critical effect
SENSITIZATION
|
Methyl ionone, mixed isomers |
R |
2008 |
2013 |
43 |
|
|
|
|
|
80-62-6
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Methyl methacrylate |
P |
|
|
43 |
|
|
|
|
|
85-91-6
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products. If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
The material has been identified for having the potential of forming nitrosamines in nitrosating systems. Downstream users therefore have to be notified of the presence of the material and its potential to be able to consider adequate protective measures.
Critical effect
PHOTOTOXICITY, POTENTIAL FOR NITROSAMINE FORMATION
|
Methyl N-methylanthranilate |
R |
2009 |
2014 |
44 |
|
|
|
|
|
53153-66-5
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
3-Methyl-2(3)-nonenenitrile |
P |
05 - 2007 |
|
43 |
|
|
|
|
|
111-80-8
Limits in the finished product (%)
| cat 1 |
0.001% - See Note Box (1) |
cat 4 |
0.002% |
cat 7 |
0.002% |
cat 10 |
0.002% |
| cat 2 |
0.001% |
cat 5 |
0.002% |
cat 8 |
0.002% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.002% |
cat 6 |
0.02% |
cat 9 |
0.002% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
When used in the same fragrance compound within a specific QRA category, the sum total of methyl octine carbonate (MOC) and methyl heptine carbonate (MHC) contributions must not exceed the maximum permitted level for MHC. At the same time, the contribution from methyl octine carbonate should always respect the maximum levels permitted as listed in the table above. If the same compound is intended for more than one IFRA QRA category, then the most restrictive limitations (based on foreseen use concentrations and maximum permitted level) will apply.
Critical effect
SENSITIZATION
|
Methyl octine carbonate |
R |
2008 |
2013 |
43 |
|
|
|
|
|
116-66-5
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Moskene (1,1,3,3,5-Pentamethyl-4,6-dinitroindane) |
P |
|
|
43 |
|
|
|
|
|
83-66-9
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
PHOTOSENSITIZATION, NEUROTOXICITY
|
Musk ambrette |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
145-39-1
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Musk tibetene (1-tert-Butyl-2,6-dinitro-3,4,5-trimethylbenzene) |
P |
|
|
43 |
|
|
|
|
|
98-95-3
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
ACUTE TOXICITY, SKIN TOXICITY
|
Nitrobenzene |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
4674-50-4
Note box
Nootkatone used as a fragrance ingredient should be at least 98% pure, with a melting point of at least 32°C. Lower purity grades may not be used as a fragrance ingredient.
Critical effect
SENSITIZATION
|
Nootkatone |
S |
08 - 2005 |
2009 |
40 |
|
|
|
|
|
90028-68-5 = Evernia prunastri extract 9000-50-4 = oils, Oakmoss resinoid 68917-10-2 =oils, Oakmoss
Limits in the finished product (%)
| cat 1 |
0.02% - See Note Box (1) |
cat 4 |
0.1% |
cat 7 |
0.1% |
cat 10 |
0.1% |
| cat 2 |
0.03% |
cat 5 |
0.1% |
cat 8 |
0.1% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.1% |
cat 6 |
0.5% |
cat 9 |
0.1% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
In the presence of tree moss extracts, the level of oak moss in the respective category has to be reduced accordingly such that the total amount of both extracts does not exceed the maximum permitted level in each category as listed in the table above.
If the same compound is intended for more than one IFRA QRA category, then the most restrictive limitation (based on foreseen use concentrations and maximum permitted level) will apply.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Oak moss extracts used in fragrance compounds must not contain added tree moss, which is a source of resin acids.
Traces of resin acids may be carried over to commercial qualities of oak moss in the manufacturing process. These traces must not exceed 0.1% (1000 ppm) dehydroabietic acid (DHA) in the extract.
The concentration of resin acids in oak moss can be measured with an HPLC Reverse Phase – spectrofluorometry method.
Further, levels of atranol and chloroatranol should each be below 100 ppm in oak moss extracts.
Critical effect
SENSITIZATION
|
Oakmoss extracts |
R |
2008 |
2013 |
43 |
|
|
|
|
|
2442-10-6
Limits in the finished product (%)
| cat 1 |
0.1% - See Note Box (1) |
cat 4 |
0.3% |
cat 7 |
0.3% |
cat 10 |
0.3% |
| cat 2 |
0.1% |
cat 5 |
0.3% |
cat 8 |
0.3% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.3% |
cat 6 |
2.5% |
cat 9 |
0.3% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
1-Octen-3-yl acetate |
R |
2008 |
2013 |
43 |
|
|
|
|
|
25677-40-1
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SENSITIZATION
|
2-Pentylidene cyclohexanone |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
8007-00-9
Note box
Restrictions on the use of Peru balsam oil, absolute and anhydrol are contained in a separate Standard (Peru balsam extracts and distillates)
Critical effect
SENSITIZATION
|
Peru balsam crude |
P |
2007 |
|
42 |
|
|
|
|
|
8007-00-9
Limits in the finished product (%)
| cat 1 |
0.03% - See Note Box (1) |
cat 4 |
0.4% |
cat 7 |
0.07% |
cat 10 |
0.4% |
| cat 2 |
0.04% |
cat 5 |
0.2% |
cat 8 |
0.4% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.1% |
cat 6 |
0.7% |
cat 9 |
0.4% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
The use of Peru balsam crude is PROHIBITED in a separate Standard.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Peru balsam extracts and distillates |
R |
2008 |
2013 |
43 |
|
|
|
|
|
122-78-1
Limits in the finished product (%)
| cat 1 |
0.02% |
cat 4 |
0.3% |
cat 7 |
0.04% |
cat 10 |
2.5% |
| cat 2 |
0.02% |
cat 5 |
0.1% |
cat 8 |
0.6% |
cat 11 |
See Note Box |
| cat 3 |
0.09% |
cat 6 |
0.4% |
cat 9 |
3% |
|
|
Note box
Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
This Standard cancels and replaces the existing one on phenylacetaldehyde, which was based on the no longer supported ‘quenching’ phenomenon.
Critical effect
SENSITIZATION
|
Phenylacetaldehyde |
R |
2006 |
2011 |
40 |
|
|
|
|
|
103-79-7
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Phenyl acetone (Methyl benzyl ketone) |
P |
|
|
43 |
|
|
|
|
|
93-99-2
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Phenyl benzoate |
P |
|
|
43 |
|
|
|
|
|
Note box
Essential oils (e.g. turpentine oil) and isolates (e.g. delta-3-carene) derived from the Pinacea family, including Pinus and Abies genera, should only be used when the level of peroxides is kept to the lowest practicable level, for instance by adding antioxidants at the time of production. Such products should have a peroxide value of less than 10 millimoles peroxide per liter, determined according to the FMA method, which can be downloaded from the IFRA website (see Analytical Methods).
Critical effect
SENSITIZATION
|
Pinacea derivatives |
S |
07 - 1994 |
|
|
|
|
|
|
|
17369-59-4
Limits in the finished product (%)
| cat 1 |
0.01% - See Note Box (1) |
cat 4 |
0.01% |
cat 7 |
0.01% |
cat 10 |
0.01% |
| cat 2 |
0.01% |
cat 5 |
0.01% |
cat 8 |
0.01% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.01% |
cat 6 |
0.7% |
cat 9 |
0.01% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
3-Propylidenephthalide |
R |
2008 |
2013 |
43 |
|
|
|
|
|
141-10-6
Note box
Pseudoionone should not be used as fragrance ingredient as such, but a level of up to 2% as an impurity in ionones is accepted.
Critical effect
SENSITIZATION
|
Pseudoionone (2,6-Dimethylundeca-2,6,8-trien-10-one) |
S |
09 - 2002 |
|
40 |
|
|
|
|
|
26651-96-7 72968-25-3 1117-41-5
Note box
Pseudo methylionones should not be used as fragrance ingredients as such, but a level of up to 2% as an impurity in methylionones is accepted.
Critical effect
SENSITIZATION
|
Pseudo methylionones |
S |
2009 |
|
44 |
|
|
|
|
|
23696-85-7 23726-93-4 43052-87-5 24720-09-0 23726-94-5 23726-92-3 23726-91-2 57378-68-4 71048-82-3 3
Limits in the finished product (%)
| cat 1 |
0.003% - See Note Box (1) |
cat 4 |
0.02% |
cat 7 |
0.008% |
cat 10 |
0.02% |
| cat 2 |
0.004% |
cat 5 |
0.02% |
cat 8 |
0.02% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.02% |
cat 6 |
0.07% |
cat 9 |
0.02% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be re-evaluated again.
The above limits apply to Rose Ketones used individually or in combination.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Rose ketones |
R |
2009 |
2014 |
44 |
|
|
|
|
|
8014-29-7
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
For applications on areas of skin exposed to sunshine, excluding bath preparations, soaps and other products which are washed off the skin, Rue oil should not be used such that the level in the consumer product exceeds 0.15% (see remark on phototoxic ingredients in the introduction to the IFRA Code of Practice).
Critical effect
PHOTOTOXICITY
|
Rue oil |
R |
04 - 2001 |
|
35 |
|
|
|
|
|
94-59-7 120-58-1 94-58-6
Note box
Safrole as such should not be used as a fragrance ingredient; essential oils containing safrole should not be used at a level such that the total concentration of safrole exceeds 0.01% in consumer products. Examples of essential oils with a high safrole content are Sassafras oil (Sassafras officinale Nees& Eberm.), Ocotea Cymbarum oil (Ocotea pretiosa Metz) and certain qualities of Camphor oils.
The total concentration of safrole, isosafrole and dihydrosafrole should not exceed 0.01% in consumer products.
|
Safrole, Isosafrole, Dihydrosafrole |
R |
07 - 1987 |
|
|
|
|
|
|
|
84961-58-0
Note box
The material had been on the list of 'other materials' before, which for reasons of a unified Standard format for prohibited materials was disbanded.
Critical effect
SEE NOTE BOX
|
Santolina oil |
P |
2006 |
|
43 |
|
|
|
|
|
8024-00-8
Note box
Savin oil should not be used as a fragrance ingredient if prepared from Juniperus Sabina L. Only oils obtained from Juniperus phoenicea L. should be used.
In the absence of an international standard, the following specificiations for oils of
Juniperus phoenicea L. are proposed:
Density d 20/20 0,864 - 0,873
Refraction n 20 D 1,4700 - 1,4720
Rotation alpha 20 D -1° - +4°
Acid value 0,4 - 1
Ester value 2,5 - 7
Ester value after acetylation 10 - 23
Solubility 0.5-6 vol. in alcohol 96%, beyond that opalescence on dilution
|
Savin oil |
S |
06 - 1982 |
|
|
|
|
|
|
|
515-03-7
Note box
Sclareol used as a fragrance ingredient should have a minimum purity of 98%.
|
Sclareol |
S |
09 - 2004 |
|
39 |
|
|
|
|
|
91722-29-1 8016-84-0
Note box
The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100.
Critical effect
PHOTOTOXICITY
|
Tagetes oil and absolute |
R |
01 - 2001 |
2006 |
39 |
|
|
|
|
|
84650-60-2
Limits in the finished product (%)
| cat 1 |
0.01% - See Note Box (1) |
cat 4 |
0.2% |
cat 7 |
0.04% |
cat 10 |
2.5% |
| cat 2 |
0.02% |
cat 5 |
0.1% |
cat 8 |
0.5% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.07% |
cat 6 |
0.3% |
cat 9 |
2.4% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Tea leaf absolute |
R |
2006 |
2011 |
40 |
|
|
|
|
|
108-88-3
Note box
The material should not be used as fragrance ingredient for any application.
The level of toluene has to be kept as low as practicable and should never exceed 100 ppm in the fragrance compound.
Critical effect
LIVER TOXICITY
|
Toluene |
P |
10 - 2003 |
|
38 |
|
|
|
|
|
90028-67-4 = Evernia furfuracea 68648-41-9 = oils, Treemoss 68917-40-8 = oils, Treemoss resinoid
Limits in the finished product (%)
| cat 1 |
0.02% - See Note Box (1) |
cat 4 |
0.1% |
cat 7 |
0.1% |
cat 10 |
0.1% |
| cat 2 |
0.03% |
cat 5 |
0.1% |
cat 8 |
0.1% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.1% |
cat 6 |
0.5% |
cat 9 |
0.1% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
In the presence of oak moss extracts, the level of tree moss in the respective category has to be reduced accordingly such that the total amount of both extracts does not exceed the maximum permitted level in each category as listed in the table above.
If the same compound is intended for more than one IFRA QRA category, then the most restrictive limitation (based on foreseen use concentrations and maximum permitted level) will apply.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)
http://www.iofiorg.org/.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Tree moss extracts shall not contain more than 0.8% of dehydroabietic acid (DHA) as a marker of 2% of total resin acids. The concentration of DHA (about 40% of the total resin acids) in tree moss can be measured with an HPLC reverse Phase - spectrofluorometry method.
Further, levels of atranol and chloroatranol should each be below 100 ppm in tree moss extracts.
Critical effect
SENSITIZATION
|
Treemoss Extracts |
R |
2008 |
2013 |
43 |
|
|
|
|
|
8024-12-2
Note box
Verbena oil from Lippia citriodora Kunth should not be used as a fragrance ingredient, based on its sensitizing and phototoxic potential. Commercial compositions of the verbena type should meet the requirements of the IFRA Standards.
Critical effect
SENSITIZATION, PHOTOXICITY
|
Verbena oil |
P |
09 - 2002 |
|
40 |
|
|
|
|
|
103694-68-4
Limits in the finished product (%)
| cat 1 |
0.28% - See Note Box (1) |
cat 4 |
4.5% |
cat 7 |
0.8% |
cat 10 |
2.5% |
| cat 2 |
0.36% |
cat 5 |
2.4% |
cat 8 |
2% |
cat 11 |
See Note Box (2) |
| cat 3 |
1.5% |
cat 6 |
7.2% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
This Standard replaces the existing one on 2,2-Dimethyl-3-(3-tolyl)propan-1-ol distributed with the 43rd Amendment, which only
contained the restrictions based on the QRA.
2,2-Dimethyl-3-(3-tolyl)propan-1-ol should only be used as a fragrance ingredient if traces of
organochlorine compounds are restricted. Total
chlorine, which can be measured by Atomic
Absorption Spectroscopy, must not exceed 25 ppm in the raw material.
Critical effect
SENSITIZATION
|
2,2-Dimethyl-3-(3-tolyl)propan-1-ol |
R |
06 - 2010 |
2015 |
45 |
|
|
|
|
|
81-14-1
Note box
Musk xylene (CAS 81-15-2), which has been prohibited for use in fragrance compounds for
environmental reasons (vPvB), can be present in musk ketone as an impurity.
Musk ketone should only be used if it contains less
than 0.1% of musk xylene.
Critical effect
SEE NOTE BOX
|
Musk ketone |
S |
06 - 2010 |
2015 |
45 |
|
|
|
|
|
8024-12-2 85116-63-8
Limits in the finished product (%)
| cat 1 |
0.05% - See Note Box (1) |
cat 4 |
0.2% |
cat 7 |
0.12% |
cat 10 |
0.2% |
| cat 2 |
0.06% |
cat 5 |
0.2% |
cat 8 |
0.2% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.2% |
cat 6 |
1.2% |
cat 9 |
0.2% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Verbena absolute (Lippia citriodora) |
R |
06 - 2010 |
2015 |
45 |
|
|
|
|
|
116-26-7
Limits in the finished product (%)
| cat 1 |
0.001% - See Note box (1) |
cat 4 |
0.005% |
cat 7 |
0.002% |
cat 10 |
0.005% |
| cat 2 |
0.001% |
cat 5 |
0.005% |
cat 8 |
0.005% |
cat 11 |
See Note box (2) |
| cat 3 |
0.004% |
cat 6 |
0.02% |
cat 9 |
0.005% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
2,6,6-Trimethylcyclohex-1,3-dienyl methanal |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
5462-06-6
Limits in the finished product (%)
| cat 1 |
0.17% - See Note box (1) |
cat 4 |
2.67% |
cat 7 |
0.45% |
cat 10 |
2.5% |
| cat 2 |
0.22% |
cat 5 |
1.4% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.89% |
cat 6 |
4.28% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
4-Methoxy-alpha-methylbenzenepropanal |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
100-52-7
Limits in the finished product (%)
| cat 1 |
0.02% - See Note box (1) |
cat 4 |
0.27% |
cat 7 |
0.05% |
cat 10 |
2.5% |
| cat 2 |
0.02% |
cat 5 |
0.14% |
cat 8 |
0.6% |
cat 11 |
See Note box (2) |
| cat 3 |
0.09% |
cat 6 |
0.43% |
cat 9 |
3% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to negligible skin contact the concentration of a fragrance ingredient should not exceed the usual concentration of the fragrance compound in the finished product.
Critical effect
SENSITIZATION
|
Benzaldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
8001-88-5 84012-15-7 85940-29-0 68917-50-0
Note box
Crude birch wood (bark) pyrolysates (oils) derived by pyrolysis (destructive distillation) of the wood or bark of Betula Pubescens, Betula Pendula, Betula Lenta or Betula Alba should not be used as a fragrance ingredient.
Only rectified (purified) birch tar oils being in compliance with the below limitations for polynuclear aromatic hydrocarbons should be used.
Limit content of polynuclear aromatic hydrocarbons (PAH) resulting from the use of rectified oils according to Good Manufacturing Practice.
Benzopyrene and 1,2-Benzanthracene are to be used as markers for PAH. If used alone or in combination with rectified Cade oil, rectified Styrax oil or rectified Opoponax oil, the total concentration of both of the markers should not exceed 1 ppb in the final product.
Critical effect
CARGINOGENICITY, GENOTOXICITY
|
Birch wood pyrolysate |
S |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
8013-10-3 90046-02-9
Note box
Crude cade oil derived by pyrolysis of the wood and twigs of Juniperus oxycedrus L. should not be used as a fragrance ingredient.
Only rectified (purified) cade oils being in compliance with the maximum limit for polynuclear aromatic hydrocarbons should be used.
Limit content of polynuclear aromatic hydrocarbons (PAH) resulting from the use of rectified oils according to Good Manufacturing Practice.
Benzopyrene and 1,2-Benzanthracene are to be used as markers for PAH. If used alone or in combination with rectified Birch tar oils, rectified Opoponax oil or rectified Styrax oil, the total concentration of both of the markers should not exceed 1 ppb in the final product.
Critical effect
CARGINOGENICITY, GENOTOXICITY
|
Cade oil |
S |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
104-55-2
Limits in the finished product (%)
| cat 1 |
0.02% - Not Restricted (1) |
cat 4 |
0.05% |
cat 7 |
0.04% |
cat 10 |
0.05% |
| cat 2 |
0.02% |
cat 5 |
0.05% |
cat 8 |
0.05% |
cat 11 |
Not Restricted (2) |
| cat 3 |
0.05% |
cat 6 |
0.4% |
cat 9 |
0.05% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
The Standard on cinnamic aldehyde covers and replaces the former existing Standards on cassia oil, cinnamon bark oil as well as cinnamic aldehyde – methyl anthranilate schiff base. The existing Standards for cinnamic aldehyde, cassia oil, cinnamic aldehyde – methyl anthranilate schiff base and cinnamon bark oil are no longer valid.
Critical effect
SENSITIZATION
|
Cinnamic aldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
5392-40-5 141-27-5 106-26-3
Limits in the finished product (%)
| cat 1 |
0.04% |
cat 4 |
0.6% |
cat 7 |
0.1% |
cat 10 |
2.5% |
| cat 2 |
0.05% |
cat 5 |
0.3% |
cat 8 |
1.4% |
cat 11 |
See Note Box |
| cat 3 |
0.2% |
cat 6 |
1% |
cat 9 |
5% |
|
|
Note box
Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
This Standard cancels and replaces the existing one on citral, which was based on the no longer supported ‘quenching’ phenomenon.
Critical effect
SENSITIZATION
|
Citral |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
122-40-7
Limits in the finished product (%)
| cat 1 |
0.7% - See Note box (1) |
cat 4 |
10.7% |
cat 7 |
1.8% |
cat 10 |
2.5% |
| cat 2 |
0.9% |
cat 5 |
5.6% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
3.6% |
cat 6 |
17.1% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Amyl cinnamic aldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
101-86-0
Limits in the finished product (%)
| cat 1 |
0.7% - See Note box (1) |
cat 4 |
10.7% |
cat 7 |
1.8% |
cat 10 |
2.5% |
| cat 2 |
0.9% |
cat 5 |
5.6% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
3.6% |
cat 6 |
17.1% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
alpha-Hexyl cinnamic aldehyde |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
119-84-6
Limits in the finished product (%)
| cat 1 |
0.029% - See Note box (1) |
cat 4 |
0.45% |
cat 7 |
0.08% |
cat 10 |
2.5% |
| cat 2 |
0.037% |
cat 5 |
0.24% |
cat 8 |
1.01% |
cat 11 |
See Note box (2) |
| cat 3 |
0.15% |
cat 6 |
0.72% |
cat 9 |
5% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Dihydrocoumarin |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
68737-61-1 (mixed isomers) 68039-49-6 68039-48-5 27939-60-2 67801-65-4 36635-35-5 68084-52-6 35145-0
Limits in the finished product (%)
| cat 1 |
0.17% - See Note box (1) |
cat 4 |
2.7% |
cat 7 |
0.45% |
cat 10 |
2.5% |
| cat 2 |
0.22% |
cat 5 |
1.4% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.89% |
cat 6 |
4.3% |
cat 9 |
5% |
|
|
Note box
The above limits apply to Dimethylcyclohexen-3-ene-1-carbaldehyde (mixed isomers) used individually or in combination.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Dimethylcyclohex-3-ene-1-carbaldehyde (mixed isomers) |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
31906-04-4 51414-25-6
Limits in the finished product (%)
| cat 1 |
0.02% - See Note box (1) |
cat 4 |
0.2% |
cat 7 |
0.02% |
cat 10 |
0.2% |
| cat 2 |
0.02% |
cat 5 |
0.2% |
cat 8 |
0.2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.2% |
cat 6 |
0.2% |
cat 9 |
0.2% |
|
|
Note box
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry - www.iofiorg.org).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
The restrictions as given for the individual categories are NOT based on the QRA but solely represent a pragmatic approach to address the specific situation for HMPCC. These pragmatic measures will be reviewed over time in view of the development of sensitization rates (clinical data) to the material.
Critical effect
SENSITIZATION
|
HMPCC |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
107-75-5
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
1% |
cat 7 |
0.4% |
cat 10 |
1% |
| cat 2 |
0.2% |
cat 5 |
1% |
cat 8 |
1% |
cat 11 |
See Note box (2) |
| cat 3 |
0.8% |
cat 6 |
3.6% |
cat 9 |
1% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). (http://www.iofiorg.org)
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
Hydroxycitronellal |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
1205-17-0
Limits in the finished product (%)
| cat 1 |
0.34% - See Note box (1) |
cat 4 |
5.3% |
cat 7 |
0.89% |
cat 10 |
2.5% |
| cat 2 |
0.43% |
cat 5 |
2.8% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
1.78% |
cat 6 |
8.6% |
cat 9 |
5% |
|
|
Note box
(1) See the IFRA Code of Practice (Appendix 8, Introduction to the IFRA Standards) regarding the Note on Oral Care Products and other products with the potential of ingestion.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
MMDHCA |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
2111-75-3
Limits in the finished product (%)
| cat 1 |
0.02% - See Note Box (1) |
cat 4 |
0.1% |
cat 7 |
0.05% |
cat 10 |
0.1% |
| cat 2 |
0.03% |
cat 5 |
0.1% |
cat 8 |
0.1% |
cat 11 |
See Note Box (2) |
| cat 3 |
0.1% |
cat 6 |
0.5% |
cat 9 |
0.1% |
|
|
Note box
For this material, for pragmatic reasons, the restricted levels allowed by the QRA for certain categories that are actually higher than those that were in place before applying the QRA, will not be implemented for now. This position will be reevaluated as appropriate in the future.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry) (http://www.iofiorg.org/).
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-Mentha-18-dien-7-al (Perilla aldehyde) |
R |
06 - 2013 |
2018 |
47 |
|
|
|
|
|
80-54-6
Limits in the finished product (%)
| cat 1 |
0.1% - See Note box (1) |
cat 4 |
1.9% |
cat 7 |
0.3% |
cat 10 |
2.5% |
| cat 2 |
0.2% |
cat 5 |
1% |
cat 8 |
2% |
cat 11 |
See Note box (2) |
| cat 3 |
0.6% |
cat 6 |
3% |
cat 9 |
2.5% |
|
|
Note box
For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.
(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry)http://www.iofiorg.org/.
(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Critical effect
SENSITIZATION
|
p-tert-Butyl-alpha-methylhydrocinnamic aldehyde (BMHCA) |
R |
06 - 2013 |
04 - 2003 |
47 |
|
|
|
|
|